Lamotrigine overdose cause skin rash and angioedema
نویسندگان
چکیده
منابع مشابه
Potentially serious Lamotrigine-related skin rash.
OBJECTIVE To report our experience with lamotrigine (LTG)-related skin rash in children with epilepsy. METHODS We identified a series of consecutive children with epilepsy treated with LTG prospectively over a 5-year period ending 1st October 2005 at King Abdul-Aziz University Hospital and King Faisal Specialist Hospital and Research Center, Jeddah, Kingdom of Saudi Arabia. RESULTS Of 207 c...
متن کاملLamotrigine-related rash: an audit
s 423 Lamotrigine-related rash: an audit I. Wang*, G. Mawer? &J. Sander’ *School of Pharmacy; University of Bradford, Bradford, UK; t David Lewis Centre for Epilepsy Cheshire, UK; $ institute of Neurology National Hospital for Neurology and Neurosurgery, London, UK Purpose: 1. To estimate the incidence of serious and non-serious rashes associated with lamotrigine (LTG) treatment. 2. To identify...
متن کاملAllergic skin rash with lamotrigine and concomitant valproate therapy: evidence for an increased risk.
Cutaneous rash is one of the commonest adverse events associated with lamotrigine. We assessed whether the risk is increased in patients receiving concomitant valproate therapy in a population of 103 adult patients with intractable epilepsy, who had lamotrigine added to their treatment. Of the 33 patients taking valproate, 10 (30%) developed a rash, whilst of the 70 not taking valproate, only 6...
متن کاملRisk of a lamotrigine-related skin rash: Current meta-analysis and postmarketing cohort analysis
PURPOSE We systematically reviewed studies to provide current evidence on the incidence and risk of skin rash in patients with LTG therapy. METHODS PubMed and Scopus databases, up to 15 March 2014 were searched to identify relevant studies. Eligible studies included prospective studies, retrospective studies and postmarketing reports, which included data of skin rash in patients with LTG ther...
متن کاملLamotrigine rechallenge after a skin rash. A combined study of open cases and a meta-analysis.
OBJECTIVE To determine the safety of lamotrigine rechallenge after a first episode of skin rash in bipolar patients. METHOD An open cases prospective study was conducted with patients who, developed a skin rash when first treated with lamotrigine, were refractory to other treatments, and were offered lamotrigine rechallenge using a different dose titration. Additionally a review was performed...
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ژورنال
عنوان ژورنال: Open Journal of Internal Medicine
سال: 2013
ISSN: 2162-5972,2162-5980
DOI: 10.4236/ojim.2013.32016